HFD-induced hepatic lipid accumulation and inflammation are decreased in Factor D deficient mouse
Abstract Excessive intake of fat causes accumulation of fat in liver, leading to non-alcoholic fatty liver disease (NAFLD).High-fat diet (HFD) upregulates the expression of Factor D, a complement pathway component, in the liver of mice.However, the functions of Factor D in liver are not well known.Therefore, the current study investigated the relat